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Epigenetic Control of Gene Expression, The University of Melbourne

4.8
Оценки: 391
Рецензии: 100

Об этом курсе

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1...

Лучшие рецензии

автор: MM

Oct 02, 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

автор: DS

Aug 25, 2018

This is an excellent course that introduces you to fundamental knowledge of several hot topics in the field of epigenetics. Dr. Blewitt herself studies X inactivation, and I learned so much!

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Рецензии: 96

автор: manoj

Nov 25, 2018

Very good and useful

автор: Hina Khalid

Nov 17, 2018

This course is well taught and some important concepts are repeated over and over again during the course so the concept lingers in the brain as if it was there already.

автор: Gloria Jemmi Christobel R

Oct 08, 2018

Excellent course

автор: Mary McPhillips

Oct 02, 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

автор: Santiago Torres

Sep 27, 2018

I enjoyed and learnt a lot about epigenetics by taking part in this great course. The content is clear and very well explained. The Professor is outstanding! Thanks

автор: Nzubechi Deborah Ezenwenyi

Sep 27, 2018

This was a very interesting and informative course.

автор: Ignacio Susín

Sep 17, 2018

If somebody bilieves tis course is gonna be an easy one, is wrong. Very detailed, well organized, clever questions. It makes you think.

автор: Heidi-Morgane ROURE

Aug 30, 2018

Great course on a very interesting subject. Well constructed, with clear explanations, nice supports, wonderful contents. I love it. The level of difficulty increases with each chapters but regurlarly, so it's relatively easy. Great teacher, she seems passionate about what she does even though it is difficult to be passionate alone in front of a camera… She sometimes end on a little opening on the researches on the subject, especially the ones done in her own lab, which I think is very interesting. Thank you for this amazing course! I recommend it to everyone interested in genetics, epigenetics or who wants to know the relatively new discoveries in the field.

автор: Dan Sun

Aug 25, 2018

This is an excellent course that introduces you to fundamental knowledge of several hot topics in the field of epigenetics. Dr. Blewitt herself studies X inactivation, and I learned so much!

автор: Vasisht Varsh Sridhar

Aug 08, 2018

A very informative course which starts from the basics and goes up all the way and the pace of the course is also perfectly set for anyone from professionals to first-timers.