In previous courses in the Specialization, we have discussed how to sequence and compare genomes. This course will cover advanced topics in finding mutations lurking within DNA and proteins.
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Об этом курсе
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Калифорнийский университет в Сан-Диего
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Программа курса: что вы изучите
Week 1: Introduction to Read Mapping
<p>Welcome to our class! We are glad that you decided to join us.</p><p>In this class, we will consider the following two central biological questions (the computational approaches needed to solve them are shown in parentheses):</p><ol><li>How Do We Locate Disease-Causing Mutations? (<em>Combinatorial Pattern Matching</em>)</li><li>Why Have Biologists Still Not Developed an HIV Vaccine? (<em>Hidden Markov Models</em>)</li></ol><p>As in previous courses, each of these two chapters is accompanied by a Bioinformatics Cartoon created by talented artist Randall Christopher and serving as a chapter header in the Specialization's bestselling <a href="http://bioinformaticsalgorithms.com" target="_blank">print companion</a>. You can find the first chapter's cartoon at the bottom of this message. </p><p><img src="https://stepic.org/media/attachments/lessons/292/chapter7_cropped.jpg" title="Image: https://stepic.org/media/attachments/lessons/292/chapter7_cropped.jpg" width="528"></p>
Week 2: The Burrows-Wheeler Transform
<p>Welcome to week 2 of the class!</p>
Week 3: Speeding Up Burrows-Wheeler Read Mapping
<p>Welcome to week 3 of class!</p>
Week 4: Introduction to Hidden Markov Models
<p>Welcome to week 4 of class!</p>
Рецензии
Лучшие отзывы о курсе ПОИСК МУТАЦИЙ В ДНК И ПРОТЕИНАХ (БИОИНФОРМАТИКА VI)
One of the best specialization on Coursera. Highly recommended for anyone who wants to apply his/her programming skills to fascinating real-world problems.
Really enjoyed this course. It was great to get to build on work from previous courses.
It was probably my favorite in this specialization (at least, out of first six).
Really loved learning about suffix trees/arrays, BWT, Pattern matching, HMMs!
Специализация Биоинформатика: общие сведения
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