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Antimicrobial resistance - theory and methods, Technical University of Denmark (DTU)

4.6
Оценки: 543
Рецензии: 134

Об этом курсе

The course will cover the topics related to antimicrobial resistance with basic definitions and overview on antimicrobials their use and the emergence and spread of resistance. The course will guide you through the concepts and the importance of resistance spread and dissemination and how that happens. It will show you how bacteria become resistant and which mechanisms they might use for this. And as part of the course you will also receive some training in methods for antimicrobial susceptibility testing (AST) and detection of specific resistance in the microbiological laboratories with the basic methods available and with focus on the obtention of good quality results which can be interpreted and used for different purposes. Additionally, it will show you how to use genomic analysis tools to analyze whole genome sequencing data to detect resistance genes (and or other genes of interest) in a simple and easy way using online tools freely available. In the new new version an additional module including detection of specific resistance mechanisms was added. After this course you should be able to: 1. Describe the most important families of antimicrobials and mode of action 2. Understand the basic concepts of antimicrobial resistance from several perspectives (clinical, research and microbiological) 3. Enumerate and describe how bacteria can become resistant and the mechanisms that may be involved in that process 4. Describe how antimicrobial resistance emerges and spreads around the world including concepts of antimicrobial resistance transfer, selection and dissemination 5. Enumerate the methods used for antimicrobial susceptibility testing (AST) 6. Compare dilution and diffusion methods and know the basic techniques of agar disk diffusion, broth dilution and agar dilution methods 7. Have detailed theoretical knowledge on how to perform the main methods in a laboratory 8. Know the basic concepts about analysis and interpretation of results of AST, including different breakpoints, cut-off setting and their applications. 9. Understand the importance and related concepts related to quality management and quality assurance method standardization, applied to AST 10. Relate the information obtained in this course with real cases of resistant bacteria spreading in patients, the community, animals or the environment 11. Relate the phenotypical results with results from genotyping using molecular techniques for detection of resistance mechanisms 12. Understand the concept and be able to apply genomic analysis tools used to detect resistance genes and other relevant genes from Whole Genome Sequencing (WGS) data (with demonstration of selected online tools) Disclaimer: Please note that the guidelines and methods referred or links included in these materials are updated when the videos lectures are produced and before the course is released, however these might become outdated with time....

Лучшие рецензии

автор: DJ

Nov 15, 2016

It was really a good lectures and please I want to know about my certificate in have already purchased this course and submitted all\n\nThe documents let me know when will I get my certificate .

автор: AA

Sep 24, 2017

This i very good course. i recommended to all microbiology and molecular biology students. All three teachers are very good. specially last week lecture about molecular detection of MRSA. CRE.

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Рецензии: 131

автор: Antonio Cogliano Allechi

Dec 06, 2018

excelente

автор: Zain Ul Abedien

Nov 26, 2018

it was really a great course and i recommend all microbiologists to take the course.

автор: Ahmed Elsayed Ahmed Eldidamony

Nov 23, 2018

Thank you so much for this information and this course

автор: vishnu m s

Nov 15, 2018

Excellent!

автор: shamsi abdullah saad shamsi

Nov 11, 2018

coursera and DTU course one of the best thing happen to my professional life

thank you all for this wonderful work

автор: Jonathan Olumuyiwa Ajayi

Nov 09, 2018

Worth the time, and very informative.

автор: JESUS DAVID SIERRA MARTINEZ

Oct 16, 2018

Es un curso excepcional, la calidad es excelente, superó mis expectativas!!!

автор: Islam mahmoud mohamed metwally

Sep 12, 2018

It was a very helpful and useful course , I enjoyed it very much , but I hope to be more questions during video as in sometimes get boring and too much information, Thanks.

автор: Yonatan Rivera Aragon

Aug 28, 2018

Very useful information, both general and specific, if a bit light on clinical applications.

автор: Kübra Bunte

Aug 20, 2018

I am a dentist, currently working in a clinic in Shanghai, China and find this course very useful for refreshing my basic knowledge about these laboratory procedures. Mrs. Cavaco is truly an excellent lecturer and a very knowledgeable scientist. I am very glad to have taken this course.

Thank you, the entire DTU team who is involved in the preparation and presentation of this great course and Coursera team for spreading the knowledge across the world.