Об этом курсе
4.8
42 ratings
10 reviews
The objective of this course is to give students the most up-to-date information on the biological, personal, and societal relevance of sleep. Personal relevance is emphasized by the fact that the single best predictor of daytime performance is the quality of the previous night's sleep. The brain actively generates sleep, and the first section of the course is an overview of the neurobiological basis of sleep control. The course provides cellular-level understanding of how sleep deprivation, jet lag, and substances such as alcohol, ,caffeine, and nicotine alter sleep and wakefulness. The second section of the course covers sleep-dependent changes in physiology and sleep disorders medicine. Particular emphasis will be placed on disorders of excessive sleepiness, insomnia, and sleep-dependent changes in autonomic control. Chronic sleep deprivation impairs immune function and may promote obesity. Deaths due to all causes are most frequent between 4:00 and 6:00 a.m., and this second section of the class highlights the relevance of sleep for preventive medicine. The societal relevance of sleep will be considered in the final section of the class. In an increasingly complex and technologically oriented society, operator-error by one individual can have a disastrous negative impact on public health and safety. Fatigue-related performance decrements are known to have contributed as causal factors to nuclear power plant failures, transportation disasters, and medical errors....
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Beginner Level

Начальный уровень

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Предполагаемая нагрузка: 5 hours/week

Прибл. 19 ч. на завершение
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English

Субтитры: English
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Только онлайн-курсы

Начните сейчас и учитесь по собственному графику.
Calendar

Гибкие сроки

Назначьте сроки сдачи в соответствии со своим графиком.
Beginner Level

Начальный уровень

Clock

Предполагаемая нагрузка: 5 hours/week

Прибл. 19 ч. на завершение
Comment Dots

English

Субтитры: English

Программа курса: что вы изучите

1

Раздел
Clock
2 ч. на завершение

Unit 01 - Neurobiology Section: Course Introduction & Neurobiology of Sleep and Wakefulness (Part One) - (Standard Track & Honors Track)

This unit begins with a Course Overview video from Ralph Lydic, Ph.D., followed by the first portion of the Neurobiology of Sleep and Wakefulness lecture, delivered by Helen Baghdoyan, Ph.D. PLEASE NOTE: Only the Course Overview video, and the Getting Started and Syllabus readings are required for students who have chosen to engage in the Standard Track portion of the course content. Standard track students may also bypass all content in units 2, 3, and 4, and instead move directly to unit 5 after viewing the Course Overview video....
Reading
6 видео (всего 93 мин.), 4 материалов для самостоятельного изучения, 1 тест
Video6 видео
02.01 - Learning Points14мин
02.02 - Defining Behavioral States8мин
02.03 - Historical Overview: Brainstem & Forebrain17мин
02.04 - Wake & REM: Monoamines17мин
02.05 - Wake & REM: Acetylcholine17мин
Reading4 материала для самостоятельного изучения
Getting Started10мин
Syllabus10мин
Help Us Learn More About You!10мин
Lesson 2 Orientation10мин
Quiz1 практическое упражнение
Did you Complete Lesson 2?2мин

2

Раздел
Clock
2 ч. на завершение

Unit 02 - Neurobiology Section: Neurobiology of Sleep and Wakefulness (Part Two) - (Honors Track)

Unit 2 continues the lecture from Helen Baghdoyan, Ph.D. on the Neurobiology of Sleep and Wakefulness. PLEASE NOTE: This content is only required for students who have chosen to pursue the Honors Track certification....
Reading
5 видео (всего 73 мин.), 2 тестов
Video5 видео
02.07: Wake & REM: Orexin17мин
02.08: NREM: GABA14мин
02.09: NREM: Adenosine 11мин
02:10: Summary12мин
Quiz2 практического упражнения
Did you complete Lesson 03?2мин
Unit 02 Honors Track Quiz - Neurobiology of Sleep and Wakefulness30мин

3

Раздел
Clock
1 ч. на завершение

Unit 03 - Neurobiology: Mathematical Modeling of Sleep-Wake Regulation - (Honors Track)

Unit 3 continues the Neurobiology section of the content with a lecture from Victoria Booth, Ph.D. on the Mathematical Modeling of Sleep-Wake Regulation. PLEASE NOTE: This content is only required for students who have chosen to pursue the Honors Track certification....
Reading
10 видео (всего 67 мин.), 1 материал для самостоятельного изучения, 2 тестов
Video10 видео
03.02 - Two Process Model 5мин
03.03 - Sleep-Wake Flip-Flop Model5мин
03.04 - Reciprocal Interaction Model 12мин
03.05 - REM Sleep Flip-Flop Model4мин
03.06 - Features for an Ideal Model of Sleep-Wake Regulation7мин
03.07 - Introduction to Mechanistic Models of Sleep-Wake Regulation 3мин
03.08 - Diniz Benh & Booth Model - Part I9мин
03.09 - Diniz Benh & Booth Model - Part II 14мин
03.10 - Conclusion 1мин
Reading1 материал для самостоятельного изучения
Unit 03 Orientation10мин
Quiz2 практического упражнения
Did you Complete Lesson 5?2мин
Unit 03 Quiz - Mathematical Modeling of Sleep-Wake Regulation10мин

4

Раздел
Clock
1 ч. на завершение

Unit 04 - Neurobiology: Molecular Biology and Genetics of Sleep - (Honors Track)

Unit 4 closes out the Neurobiology section with a lecture from Chiara Cirelli, Ph.D. on Molecular Biology and the Genetics of Sleep. PLEASE NOTE: This content is only required for students who have chosen to pursue the Honors Track certification....
Reading
6 видео (всего 52 мин.), 2 тестов
Video6 видео
04.02 - Wake Genes that are Associated with Energy Metabolism 7мин
04.03 - Synaptic Plasticity is Genetically Modulated 7мин
04.04 - Brain Glial Cells Influence States of Sleep and Wakefulness 9мин
04.05 - Genetic Modulation of Human Sleep Phenotypes 8мин
04.06 - Conclusion 11мин
Quiz2 практического упражнения
Did you complete Lesson 7?2мин
Unit 04 Quiz - Molecular Biology and Genetics of Sleep10мин
4.8

Лучшие рецензии

автор: JQJan 3rd 2018

Excellent course! A great review on stuff I should have remembered but of course have forgotten as I've aged. My thanks to those organizing and teaching the course! Dr Quincy

автор: DFFeb 19th 2018

I thoroughly enjoyed this course and look forward to continuing my education on the subject.

Преподавателя

Ralph Lydic, Ph.D.

Professor Emeritus, Molecular and Integrative Physiology, Professor Emeritus, Anesthesiology
University of Michigan Medical School

Helen Baghdoyan, Ph.D.

Professor Emeritus, Anesthesiology, Professor Emeritus, Pharmacology, Professor of Psychiatry
University of Michigan Medical School

О University of Michigan

The mission of the University of Michigan is to serve the people of Michigan and the world through preeminence in creating, communicating, preserving and applying knowledge, art, and academic values, and in developing leaders and citizens who will challenge the present and enrich the future....

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