Over 500,000 people in the United States and over 8 million people worldwide are dying from cancer every year. As people live longer, the incidence of cancer is rising worldwide, and the disease is expected to strike over 20 million people annually by 2030.
Understanding Cancer Metastasis
Университет Джонса ХопкинсаОб этом курсе
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Начальный уровень
Прибл. 5 часов на выполнение
Английский
Субтитры: Английский, Арабский
Приобретаемые навыки
CancerMolecular BiologyCancer BiologyCancer Stem Cells
Карьерные результаты учащихся
43%
начал новую карьеру, пройдя эти курсы
47%
получил значимые преимущества в карьере благодаря этому курсу
25%
стал больше зарабатывать или получил повышение
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Прибл. 5 часов на выполнение
Английский
Субтитры: Английский, Арабский
от партнера
Университет Джонса Хопкинса
The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
Программа курса: что вы изучите
1 ч. на завершение
History and Overview of Metastasis
In this first module, we'll concentrate on the history and overview of metastasis and give you a flavor of how cancer is defined as well as some of the history surrounding how we began to understand metastasis.
1 ч. на завершение
5 видео ((всего 18 мин.))
5 видео
Introduction to History and Overview of Metastasis48
History and Overview of Metastasis4мин
History of Metastasis Theory4мин
Introduction to the Sequential Steps of Metastasis5мин
1 практическое упражнение
History and Overview of Metastasis20мин
1 ч. на завершение
Primary Tumor Growth and Neoangiogenesis
In this module, we'll focus on uncontrolled cell division, which is a defining property of cancer, as well as mutation and neoangiogenesis and their roles in tumor formation. We'll also take a look at a primary tumor microenvironment and its component cell types.
1 ч. на завершение
5 видео ((всего 36 мин.))
5 видео
Tumor formation: Uncontrolled cell division12мин
The role of mutations in primary tumor formation and evolution11мин
Neoangiogenesis: new blood vessel formation in cancer5мин
The primary tumor microenvironment: what else affects primary tumor growth?6мин
1 практическое упражнение
Primary Tumor Growth and Neoangiogenesis24мин
1 ч. на завершение
EMT / Invasion / Intravasation
During this module, we'll turn our attention to the next steps after the initial primary tumor formation, epithelial to mesenchymal transition of cancer cells, and local tumor invasion and intravasation into blood or lymph vessels.
1 ч. на завершение
4 видео ((всего 18 мин.))
4 видео
Epithelial-mesenchymal transition, invasion, and intravision9мин
Local Tumor Invasion4мин
Intravasation2мин
1 практическое упражнение
Invasion and Intravasation14мин
1 ч. на завершение
Survival in the Circulation and Extravasation
We'll now take a close look at cancer survival within the circulation, the role of the circulatory system in metastasis, the genetic determinants of metastatic potential, signalling mechanisms, chemokines, the dock and lock hypothesis, and extravasation.
1 ч. на завершение
6 видео ((всего 31 мин.))
6 видео
Glossary of Terms2мин
The Circulation4мин
How cancer cells survive while in circulation4мин
Becoming a circulating tumor cell (CTC) and evading immune detection10мин
Homing to a new site in the body and extravasation8мин
1 практическое упражнение
Survival in the Circulation and Extravasation24мин
1 ч. на завершение
Dormancy and Secondary Tumor Growth
In this module, we'll focus on dormancy and secondary tumor growth and how they contribute to the lethality of cancer.
1 ч. на завершение
6 видео ((всего 31 мин.))
6 видео
Metastatic homing5мин
Evidence for cancer dormancy4мин
Cancer dormancy defined8мин
Properties of dormant cancer cells6мин
Secondary outgrowth4мин
1 практическое упражнение
Dormancy and Secondary Tumor Growth20мин
1 ч. на завершение
Morbidity and Mortality Associated with Metastasis
In the previous modules, we've looked closely at the sequential steps of metastasis and some of the biology of how metastasis occurs. Now, we'll turn our attention to morbidity and mortality, or in other words, how cancer hurts and kills people.
1 ч. на завершение
4 видео ((всего 27 мин.))
4 видео
Distribution of Metastasis: Where do cancers spread?10мин
Cancer Syndromes14мин
Congratulations1мин
1 практическое упражнение
Morbidity and Mortality Associated with Metastasis20мин
Рецензии
Лучшие отзывы о курсе UNDERSTANDING CANCER METASTASIS
от партнера MS1 июля 2020 г.
A big thanks to John Hopkins University for this course the faculty of this university is one of the best faculty i have ever seen all things are much clear and confidential. Once again Thanks.
от партнера JO26 мая 2020 г.
It was an amazing experience to be able to learn a little more about cancer metastasis with this course. One suggestion: you could make the material and references worked on in class available.
от партнера RW3 июня 2018 г.
It is a beautifully designed course. it never gets boring. The best part is that you can learn at your own pace. Thank you all the instructors and Coursera for making the content available.
от партнера MA12 янв. 2017 г.
That's was Avery good experience on the course it's really beneficial and very helpful and I want to thank doctors that had taken apart in explaining cancer metastasis thanks very much
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